Nullary

Documentation

Nullary is a structured, citable record of what didn't work in drug discovery — inactive compounds, terminated trials, failed screens, and developability dead ends — delivered through an MCP server and a REST API.

Why negative results

Failed experiments rarely get published, and when they do they're scattered across incompatible databases. That absence is expensive: teams re-run dead ends and models train only on successes. Nullary normalizes negative findings across public sources into one schema, keyed to compounds and targets, with provenance on every record.

Two ways in

Start here

  • Quickstart — your first query in two minutes.
  • Data model — modalities, finding types, outcomes, and provenance fields.
  • Live demo — search the dataset in your browser, no install.